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Consideration should be given both to the benefit of lipid lowering by use of crestor in hiv patients receiving protease inhibitors and the potential for increased rosuvastatin plasma concentrations when initiating and up titrating crestor doses in patients treated with protease inhibitors.

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in patients given rosuvastatin 40 mg, however, urinary protein excretion was not significantly different from baseline, but the patients did have a significant decrease from baseline in egfr, and doubling of serum creatinine and acute renal failure were more common in this group.

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finally, rosuvastatin at a low dose has demonstrated high efficacy for ldl-c lowering, enabling patients with hypercholesterolemia to achieve their lipid goals.

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